H2N2V1, Main, Exploration, bibRecord, 001795

En Russe

Identifieur interne : 001795 ( Main/Exploration ); précédent : 001794; suivant : 001796

En Russe

Auteurs : Yu. A. Desheva ; G. V. Danini ; E. P. Grigoryeva ; S. A. Donina ; I. V. Kiseleva ; A. R. Rekstin ; L. A. Ermakova ; V. K. Natsina ; V. M. Nikolaeva ; N. I. Lonskaya ; G. A. Elshina ; V. G. Zhavoronkov ; V. P. Drinevsky ; M. K. Erofeeva ; A. N. Naikhin ; L. G. Rudenko

Source :

Voprosy virusologii [ 0507-4088 ] ; 2002.

RBID : Pascal:03-0064497

Descripteurs français

Pascal (Inist)
- Virus grippal A, Virus grippal B, Toxicité, Immunogénicité, Vaccin, Vaccination, Enfant, Immunisation, Température, Réponse immune, Grippe.
Wicri :
- topic : Vaccin, Vaccination, Enfant.

English descriptors

KwdEn :
- Child, Immune response, Immunization, Immunogenicity, Influenza, Influenza A virus, Influenza B virus, Temperature, Toxicity, Vaccination, Vaccine.

Abstract

The study of the based on the A/Leningrad/134/17/57/(H2N2) attenuated adult live influenza vaccine (LIV) investigated features for immunization of the children, aged 3-6 years. During autumn, 1999, out of 256 children, aged 3-6 years, residents of the Leningrad region, who attended the kindergarten, 184 children were immunized with 1 or 2 doses of the live influenza vaccine, and 72 ones were given placebo. There were no any moderate or strong temperature reactions revealed after the inoculation. The LIV was shown to be genetically stable. After a single dose of the vaccine seroconversion to influenza type A virus and to influenza type B virus was observed respectively in 58% and ih 39% of seronegaive 3-6 year old vaccinees. The twofold LIV administration failed to give any advantages in stimulation of the immune response. During 6 months after immunization the morbidity rate in vaccinees did not exceed the morbidity rate in unvaccinated children. Thus LIV for adults proved safe and immunogenic and can be recommended for single dose immunization both of adults and children.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000066
to stream PascalFrancis, to step Curation: 000008
to stream PascalFrancis, to step Checkpoint: 000068
to stream Main, to step Merge: 001834
to stream Main, to step Curation: 001795

Le document en format XML

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<author><name sortKey="Grigoryeva, E P" sort="Grigoryeva, E P" uniqKey="Grigoryeva E" first="E. P." last="Grigoryeva">E. P. Grigoryeva</name>
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<author><name sortKey="Kiseleva, I V" sort="Kiseleva, I V" uniqKey="Kiseleva I" first="I. V." last="Kiseleva">I. V. Kiseleva</name>
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<author><name sortKey="Rekstin, A R" sort="Rekstin, A R" uniqKey="Rekstin A" first="A. R." last="Rekstin">A. R. Rekstin</name>
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<author><name sortKey="Ermakova, L A" sort="Ermakova, L A" uniqKey="Ermakova L" first="L. A." last="Ermakova">L. A. Ermakova</name>
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<author><name sortKey="Naikhin, A N" sort="Naikhin, A N" uniqKey="Naikhin A" first="A. N." last="Naikhin">A. N. Naikhin</name>
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<author><name sortKey="Rudenko, L G" sort="Rudenko, L G" uniqKey="Rudenko L" first="L. G." last="Rudenko">L. G. Rudenko</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="RUS" level="a">En Russe</title>
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<author><name sortKey="Zhavoronkov, V G" sort="Zhavoronkov, V G" uniqKey="Zhavoronkov V" first="V. G." last="Zhavoronkov">V. G. Zhavoronkov</name>
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<author><name sortKey="Drinevsky, V P" sort="Drinevsky, V P" uniqKey="Drinevsky V" first="V. P." last="Drinevsky">V. P. Drinevsky</name>
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<author><name sortKey="Erofeeva, M K" sort="Erofeeva, M K" uniqKey="Erofeeva M" first="M. K." last="Erofeeva">M. K. Erofeeva</name>
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<author><name sortKey="Naikhin, A N" sort="Naikhin, A N" uniqKey="Naikhin A" first="A. N." last="Naikhin">A. N. Naikhin</name>
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<author><name sortKey="Rudenko, L G" sort="Rudenko, L G" uniqKey="Rudenko L" first="L. G." last="Rudenko">L. G. Rudenko</name>
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<term>Immune response</term>
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<term>Influenza</term>
<term>Influenza A virus</term>
<term>Influenza B virus</term>
<term>Temperature</term>
<term>Toxicity</term>
<term>Vaccination</term>
<term>Vaccine</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Virus grippal A</term>
<term>Virus grippal B</term>
<term>Toxicité</term>
<term>Immunogénicité</term>
<term>Vaccin</term>
<term>Vaccination</term>
<term>Enfant</term>
<term>Immunisation</term>
<term>Température</term>
<term>Réponse immune</term>
<term>Grippe</term>
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<front><div type="abstract" xml:lang="en">The study of the based on the A/Leningrad/134/17/57/(H2N2) attenuated adult live influenza vaccine (LIV) investigated features for immunization of the children, aged 3-6 years. During autumn, 1999, out of 256 children, aged 3-6 years, residents of the Leningrad region, who attended the kindergarten, 184 children were immunized with 1 or 2 doses of the live influenza vaccine, and 72 ones were given placebo. There were no any moderate or strong temperature reactions revealed after the inoculation. The LIV was shown to be genetically stable. After a single dose of the vaccine seroconversion to influenza type A virus and to influenza type B virus was observed respectively in 58% and ih 39% of seronegaive 3-6 year old vaccinees. The twofold LIV administration failed to give any advantages in stimulation of the immune response. During 6 months after immunization the morbidity rate in vaccinees did not exceed the morbidity rate in unvaccinated children. Thus LIV for adults proved safe and immunogenic and can be recommended for single dose immunization both of adults and children.</div>
</front>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Danini, G V" sort="Danini, G V" uniqKey="Danini G" first="G. V." last="Danini">G. V. Danini</name>
<name sortKey="Desheva, Yu A" sort="Desheva, Yu A" uniqKey="Desheva Y" first="Yu. A." last="Desheva">Yu. A. Desheva</name>
<name sortKey="Donina, S A" sort="Donina, S A" uniqKey="Donina S" first="S. A." last="Donina">S. A. Donina</name>
<name sortKey="Drinevsky, V P" sort="Drinevsky, V P" uniqKey="Drinevsky V" first="V. P." last="Drinevsky">V. P. Drinevsky</name>
<name sortKey="Elshina, G A" sort="Elshina, G A" uniqKey="Elshina G" first="G. A." last="Elshina">G. A. Elshina</name>
<name sortKey="Ermakova, L A" sort="Ermakova, L A" uniqKey="Ermakova L" first="L. A." last="Ermakova">L. A. Ermakova</name>
<name sortKey="Erofeeva, M K" sort="Erofeeva, M K" uniqKey="Erofeeva M" first="M. K." last="Erofeeva">M. K. Erofeeva</name>
<name sortKey="Grigoryeva, E P" sort="Grigoryeva, E P" uniqKey="Grigoryeva E" first="E. P." last="Grigoryeva">E. P. Grigoryeva</name>
<name sortKey="Kiseleva, I V" sort="Kiseleva, I V" uniqKey="Kiseleva I" first="I. V." last="Kiseleva">I. V. Kiseleva</name>
<name sortKey="Lonskaya, N I" sort="Lonskaya, N I" uniqKey="Lonskaya N" first="N. I." last="Lonskaya">N. I. Lonskaya</name>
<name sortKey="Naikhin, A N" sort="Naikhin, A N" uniqKey="Naikhin A" first="A. N." last="Naikhin">A. N. Naikhin</name>
<name sortKey="Natsina, V K" sort="Natsina, V K" uniqKey="Natsina V" first="V. K." last="Natsina">V. K. Natsina</name>
<name sortKey="Nikolaeva, V M" sort="Nikolaeva, V M" uniqKey="Nikolaeva V" first="V. M." last="Nikolaeva">V. M. Nikolaeva</name>
<name sortKey="Rekstin, A R" sort="Rekstin, A R" uniqKey="Rekstin A" first="A. R." last="Rekstin">A. R. Rekstin</name>
<name sortKey="Rudenko, L G" sort="Rudenko, L G" uniqKey="Rudenko L" first="L. G." last="Rudenko">L. G. Rudenko</name>
<name sortKey="Zhavoronkov, V G" sort="Zhavoronkov, V G" uniqKey="Zhavoronkov V" first="V. G." last="Zhavoronkov">V. G. Zhavoronkov</name>
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{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:03-0064497
   |texte=   En Russe
}}

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	Serveur d'exploration H2N2
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Serveur d'exploration H2N2

En Russe

En Russe

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri